Drug Discovery Process

Seeing proteins as dynamic & flexible allows for a new perspective

 Discovery Process Overview

  • Review of Biology and Known Genetic Information
  • Proprietary Protein Structure Analysis
  • Identify Drug Site (orthosteric or allosteric)
  • Platform Ligand Predictions (Peptimerâ„¢ Compounds)
  • In Silico Docking & Molecular Dynamics
  • In Silico Optimization & Structure Activity Relationship (SAR)
  • Synthesis & Validation (Direct Binding / Functional)
  • From Validated Leads, Perform Medicinal Chemistry Optimization
  • Advance SAR & MOA Analysis
  • Select Clinical Candidates